Actim CRP Sensitive
Most newborns with early-onset neonatal sepsis present symptoms within the first 24 hours. Onset is most rapid in premature neonates. Culture-proven early-onset sepsis develops in about 2% of all infants with birth weight under 1,500 grams. However, ten times more infants are treated as if they are infected. Early-onset sepsis is commonly associated with micro-organisms, such as Streptococcus, Escherichia coli, Haemophilus influenza and Listeria monocytogenes, contracted from the mother while passing through the
colonized birth canal at delivery.
The normal range of CRP in the neonatal cord blood is 0.011 to 6 mg/l, and preterm babies have even lower CRP levels than term babies. As a consequence, conventional CRP methods are not sensitive enough to detect these low levels.
Actim CRP Sensitive Test
The Actim CRP Sensitive test has been developed for detecting early-onset neonatal infections especially in preterm infants. It is an immunochromato-graphic semiquantitative rapid test based on monoclonal antibodies, which makes the test highly specific to CRP. The Actim CRP Sensitive test helps medical professionals in reaching the right conclusions on the spot, detecting CRP levels as low as 0.2 mg/l.
A minute sample is enough
The Actim CRP Sensitive rapid test is easy to perform, while minimizing discomfort to the infant. All that is needed to perform the test is a tiny drop – just 10 μl – of whole blood.
Actim CRP Sensitive is not currently available in the US.
