No. Actim Partus test identifies a different phosphorylation form of IGFBP-1 than PROM test. However, the level of IGFBP-1 in amniotic fluid is so strongly elevated, that in case of leakage of amniotic fluid, Actim Partus test will give a positive result.
To correctly interpret Actim Partus result, it should be first confirmed that the fetal membranes are intact. This can be done e.g. by first performing Actim PROM test. However, if Actim Partus test is negative, the membranes are intact.
After the swab has absorbed the sample, it is transferred and extracted in the specimen extraction solution. At this point, the sample is ready for testing.
Separate samples need to be taken for the two tests. The sample for Actim Partus test must be taken from the cervix, while a vaginal sample is used for Actim PROM test.
The test requires at least 150 µl of sample to perform correctly, and this may also limit the possibility to run two dipstick tests from the same sample tube.
The dipstick should be removed from the sample as soon as the liquid front becomes visible in the result window. Appearance of the liquid front in the result window indicates that enough sample has been absorbed by the dipstick.
If the dipstick is left in the sample, the dipstick goes on absorbing the sample which in turn may lead into uncontrollable flow.
A patient with a negative test result
Can be sent home
It is highly unlikely that this patient will deliver within the next 2 weeks
Save money and hospital resources
A patient with a positive test result
Should be examined further
The risk of preterm delivery is clearly higher
After treatment (if the symptoms disappear) the patient can be tested again with Actim Partus test - if the result is negative, the patient can be sent home
Treatment can be focused on the patients who need it
A positive result can be interpreted as soon as two blue lines become visible in the result window.
However a negative test must be confirmed at 5 minutes. As the immunochromatography reaction continues to develop over time, the lines may become stronger or even new lines may appear in the result area. These lines must not be interpreted as positive as they indicate analyte levels below the detection limit of the test.
The result is interpreted by counting the number of lines in the result area. No attention should be paid to the relative intensities of the control and test lines.
The control line confirms correct performance of the test. If the control line does not appear, the test result is invalid and should be repeated with another dipstick.