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Anti-hCG beta 5011 SPRN-5

Catalog Number: 101000

Key Features

Liquid, may turn slightly opaque during storage

Human

CLIA, FIA

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Key Documents

Product Overview
Product Name Anti-hCG beta 5011 SPRN-5
Catalog Number 101000
Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
Application CLIA, FIA
Further Specification
Form/Appearance Liquid, may turn slightly opaque during storage
Concentration 5.0 mg/ml (+/- 10 %)
Isotype IgG1
Clonality Monoclonal
Epitope The antibody recognizes both intact hCG and free β subunit. It does not recognize hCGβ core fragment, as described in Berger et al (2013).
Purity ≥ 95 %
Affinity constant hCG: KA= 5.5 x 109 1/M; KD= 1.8 x 10-10 M (= 0.18 nM)
hCGβ: KA= 1.8 x 109 1/M; KD= 5.7 x 10-10 M (= 0.57 nM)
Associated Products

Native hCG antigens 189-10 and 189-11, Native β-hCG antigen 325-11

Buffer 29 mM citrate, 142 mM phosphate, pH 6.5, 0.9 % NaCI, 0.095 % NaN3 as a preservative
IEF Profile 5.5–7.0
Cross Reactivity Does not recognize LH
Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
Storage and Shipping
Storage +2-8°C
Shipping Cold packs
Shelf Life 36 months
References
References Berger, P., Paus, E., Hemken, P.M., Sturgeon, C., Stewart, W.W., Skinner, J.P., Harwick, L.C., Saldana, S.C., Ramsay, C.S., Rupprecht, K.R., Olsen, K.H., Bidart, J.M. and Stenman, U.H. (2013) Candidate epitopes for measurement of hCG and related molecules: the second ISOBM TD-7 workshop. Tumor Biol., 34: 4033-4057