MedixMAB™ antibodies & MedixAntigens™

Hormones

Technical Note Hormones

Technical Note Hormones Medix Biochemica (updated 06/2020)

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Hormones are signalling molecules secreted by glands (endocrine signalling system) for communication between organs and tissues for physiological regulation and behaviour. They affect their target cells by binding to a specific receptor to activate a signal transduction pathway. Upon secretion, certain hormones are water-soluble and are readily transported through the circulatory system, while others are lipid-soluble and need transportation through carrier plasma glycoproteins.

Alpha subunit

The alpha subunit of LH, FSH, TSH, and HCG is identical. The biological activity of these hormones is evoked by the unique beta subunit.

Monoclonal Antibodies

    Anti-h Alpha Subunit 5501 SP-1 100035 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100035
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5–7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.9 x 106 1/Ms
    Dissociation rate constant 1.1 x 10-3 1/s
    Affinity constant KA = 1.7 x 109 1/M; KD = 5.7 x 10-10 M (= 0.57 nM)
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    Anti-h Alpha Subunit 5503 SP-1 100037 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100037
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 6 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6–8.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.7 x 106 1/Ms
    Dissociation rate constant 5.3 x 10-4 1/s
    Affinity constant KA = 3.2 x 109 1/M; KD = 3.2 x 10-10 M (= 0.32 nM)     
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    Anti-h Alpha Subunit 6601 SPR-5 100066 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100066
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6–7.4
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant 8.9 x 105 1/Ms
    Dissociation rate constant 3.8 x 10-5 1/s
    Affinity constant KA = 2.4 x 109 1/M; KD = 4.2 x 10-11 M (= 0.04 nM)     
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AMH

Anti-Müllerian Hormone (AMH) is a glycoprotein produced by the Sertoli cells of the testis and by the granulosa cells of the ovary. It is used as biomarker to assess ovarian reserve levels.

Monoclonal Antibodies

    Anti-h AMH 11301 SPTN-5 100756 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100756
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5–6.9
    Purity ≥ 95 %Kinetic parameters
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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    Anti-h AMH 11302 SPTN-5 100757 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100757
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.7–5.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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    Anti-h AMH 11303 SPTN-5 100758 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100758
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.4–7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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    Anti-h AMH 11304 SPTN-5 100759 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100759
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.1–6.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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    Anti-h AMH 11305 SPTN-5 100760 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100760
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6–7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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    Anti-h AMH 11309 SPTN-5 New 100840 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100840
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.9–7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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hCG

Chorionic gonadotropin (HCG) is a glycoprotein hormone produced during pregnancy and commonly utilized for early pregnancy testing. Testing for HCG may also be done when diagnosing or monitoring some tumors.

Monoclonal Antibodies

    Anti-hCG beta 5004 SP-1 100004 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100004
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5–7.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 2.0 x 106 1/Ms and hCGβ: 5.0 x 105 1/Ms
    Dissociation rate constant hCG: 3.7 x 10-5 1/s and hCGβ: 1.2 x 10-4 1/s
    Affinity constant hCG: KA = 5.3 x 1010 1/M; KD = 1.9 x 10-11 M (= 0.02 nM)hCGβ: KA = 4.3 x 109 1/M; KD = 2.3 x 10-10 M (= 0.23 nM)
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    Anti-hCG beta 5006 SP-5 100005 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100005
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.2–7.4
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 5.7 x 106 1/Ms and hCGβ: 2.3 x 106 1/Ms
    Dissociation rate constant hCG: 2.9 x 10-4 1/s and hCGβ: 4.8 x 10-4 1/s
    Affinity constant hCG: KA = 2.0 x 1010 1/M; KD = 5.0 x 10-11 M (= 0.05 nM)hCGβ: KA = 4.8 x 109 1/M; KD = 2.1 x 10-10 M (= 0.21 nM)
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    Anti-hCG beta 5008 SP-5 100006 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100006
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 – 7.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 4.0 x 106 1/Ms and hCGβ: 1.6 x 106 1/Ms
    Dissociation rate constant hCG: 1.4 x 10-4 1/s and hCGβ: 3.6 x 10-4 1/s
    Affinity constant hCG: KA = 2.9 x 1010 1/M; KD = 3.4 x 10-11 M (= 0.03 nM)hCGb: KA = 4.4 x 109 1/M; KD = 2.3 x 10-10 M (= 0.23 nM)
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    Anti-hCG beta 5009 SP-5 100008 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100008
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 18 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3–6.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.1 x 106 1/Ms
    Dissociation rate constant 3.1 x 10-4 1/s
    Affinity constant KA = 3.6 x 109 1/M; KD = 2.8 x 10-10 M (= 0.28 nM)
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    Anti-hCG beta 5011 SPRN-1 100009 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100009
    Product buffer solution 29 mM citrate, 142 mM phosphate, pH 6.5, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.5–7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 2.4 x 106 1/Ms and hCGβ: 1.9 x 106 1/Ms
    Dissociation rate constant hCG: 4.4 x 10-4 1/s and hCGβ: 1.1 x 10-3 1/s
    Affinity constant hCG: KA = 5.5 x 109 1/M; KD = 1.8 x 10-10 M (= 0.18 nM)hCGβ: KA = 1.8 x 109 1/M; KD = 5.7 x 10-10 M (= 0.57 nM)
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    Anti-hCG beta 5012 SPRN-5 100368 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100368
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3–7.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 2.1 x 104 1/Ms
    Dissociation rate constant 1.7 x 10-4 1/s
    Affinity constant KA = 1.2 x 109 1/M; KD = 8.1 x 10-10 M (= 0.81 nM)
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    Anti-hCG 5014 SPTN-5 100011 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100011
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.4–7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 2.5 x 105 1/Ms and hCGβ: 2.8 x 105 1/Ms
    Dissociation rate constant hCG: 1.5 x 10-4 1/s and hCGβ: 2.8 x 10-4 1/s
    Affinity constant hCG: KA = 1.6 x 109 1/M; KD = 6.1 x 10-10 M (= 0.61 nM)hCGβ: KA = 9.9 x 108 1/M; KD = 1.0 x 10-9 M (= 1.0 nM)
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    Anti-hCG 5016 SPRN-5 100013 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100013
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.2–6.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 1.5 x 106 1/Ms and hCGβ: 1.9 x 106 1/Ms
    Dissociation rate constant hCG: 9.5 x 10-4 1/s and hCGβ: 5.2 x 10-3 1/s
    Affinity constant hCG: KA = 1.6 x 109 1/M; KD = 6.4 x 10-10 M (= 0.64 nM)hCGβ: KA = 3.5 x 108 1/M; KD = 2.8 x 10-9 M (= 2.8 nM)
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Estradiol

Estradiol (E2) is a steroid, and the primary female sex hormone produced by the ovaries. It prepares the uterus for implantation of the fertilized ovum and promotes maintenance of the female reproductive organs. Serum estradiol is measured in women and it primarily reflects the activity of the ovaries.

Monoclonal Antibodies

    Anti-h E2 (Estradiol) 10450 700011 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human estradiol (E2)
    Description Monoclonal antibody raised against human 17b Estradiol. In vitro cultured mouse monoclonal antibody.
    Product code 700011
    Product buffer solution 0.1 M PBS, pH 7.4, 0.9 % NaCl, 0.05 % NaN3 as a preservative
    Shelf life and storage 60 months from manufacturing at 2–8 °C
    Product concentration > 1.0 mg/ml
    Immunoreactivity Not Determined (N/D)
    IEF profile N/D
    Purity N/D
    Subclass IgG1
    Association rate constant N/D
    Dissociation rate constant N/D
    Affinity constant N/D
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Synthetic Antigens

FSH

Follicle-stimulating hormone (FSH) regulates the development, growth, pubertal maturation, and reproductive processes of the body. It is used to diagnose problems in the reproductive system.

Monoclonal Antibodies

    Anti-h FSH 6602 SP-5 100067 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human follicle-stimulating hormone (FSH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100067
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6–7.4
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 3 x 1010 1/M
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Growth hormone

Growth hormone (GH) is a protein hormone used clinically to diagnose and treat children’s growth disorders and adult growth hormone deficiency.

Monoclonal Antibodies

    Anti-h GH 5801 SP-1 100041 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human growth hormone (GH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100041
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.1–7.4
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant KA = 2 x 1010 1/M
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    Anti-h GH 5802 SP-1 100042 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human growth hormone (GH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100042
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.0–7.1
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant KA = 1 x 1010 1/M
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Inhibin A

Inhibin alpha binds to either beta A or beta B subunit, to form inhibin A, or inhibin B, respectively. Inhibin A tests can be used in the diagnostics of Down syndrome. Inhibin B is a marker of male infertility. Inhibin beta A can form dimers with itself, with inhibin alpha, or inhibin beta B. The dimerization product with inhibin alpha subunit is called inhibin A. Assessment of inhibin A concentration is used in prenatal screening for Down syndrome.

Monoclonal Antibodies

    Anti-h Inhibin alpha 9401 SPTN-5 100711 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human inhibin alpha subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100711
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3–7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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    Anti-h Inhibin beta A 9504 SPTN-5 100709 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human inhibin beta A subunit, also known as activin beta A.
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100709
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.1–8.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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LH

Luteinizing hormone (LH) is essential for reproduction in both sexes. LH is measured to detect abnormalities in sexual development and reproductive functions.

Monoclonal Antibodies

    Anti-h LH 5301 SP-5 100016 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human luteinizing hormone (lutropin), and its beta-subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100016
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3–7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 5.8 x 106 1/Ms
    Dissociation rate constant 1.3 x 10-5 1/s
    Affinity constant KA = 4.4 x 1011 1/M; KD = 2.3 x 10-12 M ( = 2.3 pM)
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    Anti-h LH 5302 SP-1 100018 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human luteinizing hormone (lutropin), and its beta-subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100018
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.6–6.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.3 x 106 1/Ms
    Dissociation rate constant 2.6 x 10-5 1/s
    Affinity constant KA = 4.8 x 1010 1/M; KD = 2.1 x 10-11 M ( = 21 pM)
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    Anti-h LH 5303 SPRN-5 100588 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human luteinizing hormone (lutropin)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100588
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5–7.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 5.4 x 106 1/Ms
    Dissociation rate constant 3.4 x 10-5 1/s
    Affinity constant KA = 1.6 x 1011 1/M; KD = 6.3 x 10-12 M ( = 6.3 pM)
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    Anti-h LH 5304 SP-5 100022 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human luteinizing hormone (lutropin), and its beta-subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100022
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.6–6.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 4.7 x 106 1/Ms
    Dissociation rate constant 1.6 x 10-5 1/s
    Affinity constant KA = 2.9 x 1011 1/M; KD = 3.4 x 10-12 M ( = 3.4 pM)
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Progesterone

Progesterone (PR) is a steroid hormone needed for normal reproduction. Progesterone levels are monitored during pregnancy and for an indication of ovarian cancer.

Monoclonal Antibodies

    Anti-Progesterone 1801 SPTNZ-5 100248 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes progesterone
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100248
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.05 % Sulfobetaine, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.8–7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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    Anti-Progesterone 1802 SPTNZ-5 100249 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes progesterone
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100249
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.05 % Sulfobetaine, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.1–8.5
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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    Anti-Progesterone 1803 SPTNZ-5 100250 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes progesterone
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100250
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.05 % Sulfobetaine, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3–7.5
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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    Anti-Progesterone 1805 SPTNZ-5 100252 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes progesterone
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100252
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.05 % Sulfobetaine, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.9–8.2
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
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PRL

Prolactin (PRL) is a peptide hormone primarily associated with lactation. Prolactin is usually measured when checking for pituitary tumors or the cause of abnormal milk production.

Monoclonal Antibodies

    Anti-h PRL 5601 SP-1 100038 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human prolactin (luteotropic hormone, or luteotropin)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100038
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.4–7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 2.6 x 1010 1/M
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    Anti-h PRL 5602 SP-5 100360 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human prolactin (luteotropic hormone, or luteotropin)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100360
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.7–6.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 9.5 x 109 1/M
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SHBG

Sex hormone-binding globulin (SHBG) binds to sex hormones, specifically testosterone and estradiol. Abnormally low or high SHBG levels are used to diagnose several non-physiological conditions.

Monoclonal Antibodies

    Anti-h SHBG 6001 SP-5 100539 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human sex hormone-binding globulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100539
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.2–6.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant kon = 4.1 x 105 1/Ms
    Dissociation rate constant koff = 4.7 x 10-5 1/s
    Affinity constant KA = 8.8 x 109 1/M; KD = 1.2 x 10-10 M (=0.12 nM)
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    Anti-h SHBG 6002 SP-5 100540 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human sex hormone-binding globulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100540
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6–7.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant kon = 1.5 x 105 1/Ms
    Dissociation rate constant koff = 1.0 x 10-4 1/s
    Affinity constant KA = 1.5 x 109 1/M; KD = 6.8 x 10-10 M (=0.68 nM)
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    Anti-h SHBG 6007 SP-5 100569 Specifications (pdf) Request sample
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human sex hormone-binding globulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100569
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.0–6.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant kon = 1.2 x 105 1/Ms
    Dissociation rate constant koff = 2.3 x 10-4 1/s
    Affinity constant KA = 0.5 x 109 1/M; KD = 1.9 x 10-9 M (=1.9 nM)
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