MedixMAB™ antibodies & MedixAntigens™

Hormones

Hormones technical note

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Hormones are signalling molecules secreted by glands (endocrine signalling system) for communication between organs and tissues for physiological regulation and behaviour. They affect their target cells by binding to a specific receptor to activate a signal transduction pathway. Upon secretion, certain hormones are water-soluble and are readily transported through the circulatory system, while others are lipid-soluble and need transportation through carrier plasma glycoproteins.

Alpha subunit

Alpha subunit The alpha subunit of LH, FSH, TSH, and HCG is identical. The biological activity of these hormones is evoked by the unique beta subunit.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100035
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °CAnalyte descriptionThe alpha subunits of gonadotropins LH, FSH, TSH, and hCG are identical. The human alpha subunit consists of 92 amino acids, and has an average molecular weight of 14 kDa.
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 – 7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.9 x 106 1/Ms
    Dissociation rate constant 1.1 x 10-3
    Affinity constant KA = 1.7 x 109 1/M; KD = 5.7 x 10-10 M (= 0.57 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100037
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 6 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 – 8.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.7 x 106 1/Ms
    Dissociation rate constant 5.3 x 10-4 1/s
    Affinity constant KA = 3.2 x 109 1/M; KD = 3.2 x 10-10 M (= 0.32 nM)     
    Type Monoclonal Antibodies
    Specificity Antibody recognizes the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100066
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 – 7.4
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant 8.9 x 105
    Dissociation rate constant 3.8 x 10-5
    Affinity constant KA = 2.4 x 109 1/M; KD = 4.2 x 10-11 M (= 0.04 nM)

AMH

Anti-Müllerian Hormone (AMH) is a glycoprotein produced by the Sertoli cells of the testis and by the granulosa cells of the ovary. It is used as biomarker to assess ovarian reserve levels.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100756
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 - 6.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100757
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.7 - 5.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100758
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 - 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100759
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.1 - 6.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human anti-Müllerian hormone (AMH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100760
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 - 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D

hCG

Chorionic gonadotropin (HCG) is a glycoprotein hormone produced during pregnancy and commonly utilized for early pregnancy testing. Testing for HCG may also be done when diagnosing or monitoring some tumors.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100004
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 - 7.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 2.0 x 106 1/Ms and hCGβ: 5.0 x 105 1/Ms
    Dissociation rate constant hCG: 3.7 x 10-5 1/s and hCGβ: 1.2 x 10-4 1/s
    Affinity constant hCG: KA = 5.3 x 1010 1/M; KD = 1.9 x 10-11 M (= 0.02 nM)hCGβ: KA = 4.3 x 109 1/M; KD = 2.3 x 10-10 M (= 0.23 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100005
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 – 7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 5.7 x 106 1/Ms and hCGβ: 2.3 x 106 1/Ms
    Dissociation rate constant hCG: 2.9 x 10-4 1/s and hCGβ: 4.8 x 10-4
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100006
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 – 7.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 4.0 x 106 1/Ms and hCGβ: 1.6 x 106 1/Ms
    Dissociation rate constant hCG: 1.4 x 10-4 1/s and hCGβ: 3.6 x 10-4 1/s
    Affinity constant hCG: KA = 2.9 x 1010 1/M; KD = 3.4 x 10-11 M (= 0.03 nM)hCGb: KA = 4.4 x 109 1/M; KD = 2.3 x 10-10 M (= 0.23 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100008
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 18 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 – 6.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.1 x 106 1/Ms
    Dissociation rate constant 3.1 x 10-4 1/s
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100009
    Product buffer solution 29 mM citrate, 142 mM phosphate, pH 6.5, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.5 - 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 2.4 x 106 1/Ms and hCGβ: 1.9 x 106 1/Ms
    Dissociation rate constant hCG: 4.4 x 10-4 1/s and hCGβ: 1.1 x 10-3 1/s
    Affinity constant hCG: KA = 5.5 x 109 1/M; KD = 1.8 x 10-10 M (= 0.18 nM)hCGβ: KA = 1.8 x 109 1/M; KD = 5.7 x 1010 M (= 0,57 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100368     
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 – 7.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 2.1 x 104 1/Ms
    Dissociation rate constant 1.7 x 10-4
    Affinity constant KA = 1.2 x 109 1/M; KD = 8.1 x 10-10 M (= 0.81 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100011
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.4 – 7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 2.5 x 105 1/Ms and hCGβ: 2.8 x 105 1/Ms
    Dissociation rate constant hCG: 1.5 x 10-4 1/s and hCGβ: 2.8 x 10-4 1/s
    Affinity constant hCG: KA = 1.6 x 109 1/M; KD = 6.1 x 10-10 M (= 0.61 nM)hCGβ: KA = 9.9 x 108 1/M; KD = 1.0 x 10-9 M (= 1.0 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100013
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.2 – 6.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant hCG: 1.5 x 106 1/Ms and hCGβ: 1.9 x 106
    Dissociation rate constant hCG: 9.5 x 10-4 1/s and hCGβ: 5.2 x 10-3

Estradiol

Estradiol (E2) is a steroid, and the primary female sex hormone produced by the ovaries. It prepares the uterus for implantation of the fertilized ovum and promotes maintenance of the female reproductive organs. Serum estradiol is measured in women and it primarily reflects the activity of the ovaries.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human estradiol (E2)
    Description Monoclonal antibody raised against human 17b Estradiol. In vitro cultured mouse monoclonal antibody.
    Product code 700011
    Product buffer solution 0.1 M PBS, pH 7.4, 0.9 % NaCl, 0.05 % NaN3 as a preservative
    Shelf life and storage 60 months from manufacturing at 2–8 °C
    Product concentration > 1.0 mg/ml
    Immunoreactivity Not Determined (N/D)
    IEF profile N/D
    Purity N/D
    Subclass IgG1
    Association rate constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human estradiol (E2)
    Description Monoclonal antibody raised against human 17b Estradiol. In vitro cultured mouse monoclonal antibody.
    Product code 700012
    Product buffer solution 0.1 M PBS, pH 7.4, 0.9 % NaCl, 0.05 % NaN3 as a preservative
    Shelf life and storage 60 months from manufacturing at 2–8 °C
    Product concentration > 1 mg/ml
    Immunoreactivity Not Determined (N/D)
    IEF profile N/D
    Purity N/D
    Subclass IgG1
    Association rate constant N/D

Synthetic Antigens

FSH

Follicle-stimulating hormone (FSH) regulates the development, growth, pubertal maturation, and reproductive processes of the body. It is used to diagnose problems in the reproductive system.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human follicle-stimulating hormone (FSH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100067
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.7 – 7.4
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 3 x 1010 l/mol

Growth hormone

Growth hormone (GH) is a protein hormone used clinically to diagnose and treat children’s growth disorders and adult growth hormone deficiency.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human growth hormone (GH)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100041     
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.1 – 7.4
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 2 x 1010 l/mol
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human growth hormone (GH)     
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100042     
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.0 - 7.1
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 1 x 1010 l/mol

Inhibin A

Inhibin alpha binds to either beta A or beta B subunit, to form inhibin A, or inhibin B, respectively. Inhibin A tests can be used in the diagnostics of Down syndrome. Inhibin B is a marker of male infertility. Inhibin beta A can form dimers with itself, with inhibin alpha, or inhibin beta B. The dimerization product with inhibin alpha subunit is called inhibin A. Assessment of inhibin A concentration is used in prenatal screening for Down syndrome.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human inhibin alpha subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100711
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 - 7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human inhibin beta A subunit, also known as activin beta A.
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100709
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.1 - 8.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D

LH

Luteinizing hormone (LH) is essential for reproduction in both sexes. LH is measured to detect abnormalities in sexual development and reproductive functions.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human luteinizing hormone (lutropin), and its beta-subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100016
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 - 7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 5.8 x 106 1/Ms
    Dissociation rate constant 1.3 x 10-5 1/s
    Affinity constant KA = 4.4 x 1011 1/M; KD = 2.3 x 10-12 M (= 2.3 pM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human luteinizing hormone (lutropin), and its beta-subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100022
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.6 – 6.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 4.7 x 106 1/Ms
    Dissociation rate constant 1.6 x 10-5 1/s
    Affinity constant KA = 2.9 x 1011 1/M; KD = 3.4 x 10-12 M (= 3.4 pM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human luteinizing hormone (lutropin), and its beta-subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100018
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.6 – 6.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.3 x 106 1/Ms
    Dissociation rate constant 2.6 x 10-5 1/s
    Affinity constant KA = 4.8 x 1010 1/M; KD = 2.1 x 10-11 M (= 21 pM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human luteinizing hormone (lutropin)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100588
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.9 – 7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 5.4 x 106 1/Ms
    Dissociation rate constant 3.4 x 10-5 1/s
    Affinity constant KA = 1.6 x 1011 1/M; KD = 6.3 x 10-12 M (= 6.3 pM)

Progesterone

Progesterone (PR) is a steroid hormone needed for normal reproduction. Progesterone levels are monitored during pregnancy and for an indication of ovarian cancer.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes progesterone
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100248
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.05% Sulfobetaine, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.8 – 7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes progesterone
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100249
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.05 % Sulfobetaine, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.4 – 8.6
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes progesterone
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100250
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.05 % Sulfobetaine, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 – 7.5
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes progesterone
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100252
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.05 % Sulfobetaine, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.9 – 8.2
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D

PRL

Prolactin (PRL) is a peptide hormone primarily associated with lactation. Prolactin is usually measured when checking for pituitary tumors or the cause of abnormal milk production.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human prolactin (luteotropic hormone, or luteotropin)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100038
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.4 – 7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 2.6 x 1010 l/mol
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human prolactin (luteotropic hormone, or luteotropin)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100360
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.7 – 6.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 9.5 x 109 l/mol

SHBG

Sex hormone-binding globulin (SHBG) binds to sex hormones, specifically testosterone and estradiol. Abnormally low or high SHBG levels are used to diagnose several non-physiological conditions.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human sex hormone-binding globulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100539
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.2 – 6.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant kon = 4.1 x 105 1/Ms
    Dissociation rate constant koff = 4.7 x 10-5 1/s
    Affinity constant KA = 8.8 x 109 1/M; KD = 1.2 x 10-10 M (=0.12 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human sex hormone-binding globulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100540
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 – 7.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant kon = 1.5 x 105 1/Ms
    Dissociation rate constant koff = 1.0 x 10-4 1/s
    Affinity constant KA = 1.5 x 109 1/M; KD = 6.8 x 10-10 M (=0.68 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human sex hormone-binding globulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100569
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.0 – 6.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D

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