MedixMAB™ antibodies & MedixAntigens™

Inflammation

MedixMAB™ Inflammation techical note

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Inflammation is the body’s generic response to pathogens, irritants, or damaged cells, and it is considered a hallmark of the innate immune response. Its function is to eliminate the initial causes of cell damage, to remove necrotic cells and tissues and to initiate tissue repair. The increased supply of neutrophils and macrophages assist in the process. Subdued inflammation could lead to progressive tissue destruction caused by the harmful stimulus. Persistent, chronic inflammation leads to a shift in cell types such as mononuclear cells at the inflammation site, and may lead to diseases like allergies, atherosclerosis, cancer, neurodegenerative or autoimmune diseases.

AAT

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human Alpha 1-antitrypsin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100209
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.7 – 7.7
    Purity ≥ 95 %
    Subclass IgG2b
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human Alpha 1-antitrypsin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100210
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.7 – 7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D

CRP

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human C-reactive protein (CRP), binding is Ca2+ independent
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100145
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/– 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.7 – 7.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 7.3 x 105 1/Ms
    Dissociation rate constant 1.2 x 10-4 1/s
    Affinity constant KA = 6.2 x 109 1/M; KD = 1.6 x 10-10 M (= 0.16 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human C-reactive protein (CRP), binding is Ca2+ independent
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100146
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/– 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.9 – 6.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 9.6 x 105 1/Ms
    Dissociation rate constant 1.6 x 10-4 1/s
    Affinity constant KA = 6.2 x 109 1/M; KD = 1.6 x 10-10 M (= 0.16 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human C-reactive protein
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100058
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 2.0-2.5 mg/ml
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.7 – 6.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 7.7 x 106 1/Ms
    Dissociation rate constant 4.1 x 10-4 1/s
    Affinity constant KA = 1.4 x 1010 1/M; KD = 5.3 x 10-11 M (= 0.05 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human C-reactive protein
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100061
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration > 6 mg/ml
    Immunoreactivity 80–120 % compared to the reference sample in an FIA tests
    IEF profile 5.7 – 6.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 7.7 x 106 1/Ms
    Dissociation rate constant 4.1 x 10-4 1/s
    Affinity constant KA = 1.4 x 1010 1/M; KD = 5.3 x 10-11 M (= 0.05 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human C-reactive protein
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100358
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 18 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/– 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.8 – 7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 2.6 x 106 1/Ms
    Dissociation rate constant 6.6 x 10-5 1/s
    Affinity constant KA = 3.9 x 1010 1/M; KD = 2.6 x 10-11 M (= 0.03 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human C-reactive protein (CRP), binding is Ca2+ independent
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100147
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/– 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 – 7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.1 x 106 1/Ms
    Dissociation rate constant 1.3 x 10-4 1/s
    Affinity constant KA = 8.9 x 109 1/M; KD = 1.1 x 10-10 M (= 0.11 nM)

Calprotectin

Calprotectin leaflet

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Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes calprotectin S100A9 subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100460
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.2 – 8.7
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant 1.9 x 106 1/Ms
    Dissociation rate constant 9.1 x 10-4 1/s
    Affinity constant KA = 2.0 x 109 1/M; KD = 4.8 x 10-10 M (=0.5 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes calprotectin S100A8 subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100468
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 - 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 4.8 x 105 1/Ms
    Dissociation rate constant 6.1 x 10-5 1/s
    Affinity constant KA = 7.8 x 109 1/M; KD = 1.3 x 10-10 M (=0.13 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes calprotectin S100A8 subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100469
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.2 – 5.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 7.4 x 105 1/Ms
    Dissociation rate constant 1.5 x 10-4 1/s
    Affinity constant KA = 4.9 x 109 1/M; KD = 2.0 x 10-10 M (=0.2 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes calprotectin S100A8 subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100470
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.8 - 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 7.6 x 105 1/Ms
    Dissociation rate constant 1.1 x 10-4 1/s
    Affinity constant KA = 6.9 x 109 1/M; KD = 1.4 x 10-10 M (=0.14 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes calprotectin S100A8/S100A9 complex
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100618
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.8 - 7.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 4.0 x 104 1/Ms
    Dissociation rate constant 5.0 x 10-5 1/s
    Affinity constant KA = 8.0 x 108 1/M; KD = 1.3 x 10-9 M (=1.3 nM)

Recombinant Antigens

    Type Recombinant Antigens
    Description Recombinant human calprotectin heterotetramer (S100A8/S100A9) protein with an N-terminal histidine tag in the S100A8 subunit. Predicted molecular weights: S100A8 12 kDa, S100A9 13 kDa.
    Product code 610061
    Shelf life and storage Shelf life unspecified, storage at 2-8 °C
    Product concentration 0.5 mg/ml when reconstituted with 200 µl of deionized water      
    Purity SDS-PAGE
    Type Recombinant Antigens
    Description Recombinant human S100 calcium binding protein A8 antigen is produced by E.coli expression system and the target gene encoding Met1-Glu93 is expressed with a 6His tag at the C-terminus. Predicted molecular weight: 14 kDa.     
    Product code 710018
    Product concentration 0.5 mg/ml when reconstituted with 100 µl of deionized water 
    Purity SDS-PAGE > 90 %
    Type Recombinant Antigens
    Description Recombinant human S100 calcium binding protein A8 antigen is produced by E.coli expression system and the target gene encoding Met1-Glu93 is expressed with a 6His tag at the C-terminus. Predicted molecular weight: 14 kDa.
    Product code 710035
    Product buffer solution 20 mM HEPES, pH 7.4, 150 mM NaCl
    Shelf life and storage -20 °C
    Product concentration 0.5 mg/ml when reconstituted with 1000 µl of deionized water
    Purity SDS-PAGE > 90 %
    Type Recombinant Antigens
    Description Recombinant human S100 calcium binding protein A8 antigen is produced by E.coli expression system and the target gene encoding Met1-Glu93 is expressed with a 6His tag at the C-terminus. Predicted molecular weight: 14 kDa.  
    Product code 710034
    Shelf life and storage -20 °C
    Product concentration 0.5 mg/ml when reconstituted with 2000 µl of deionized water
    Purity SDS-PAGE > 90 %
    Type Recombinant Antigens
    Description Recombinant human S100 calcium binding protein A9 antigen is produced by E.coli expression system and the target gene encoding Thr2-Pro114 is expressed. Predicted molecular weight: 13 kDa.
    Product code 710019
    Product concentration 0.5 mg/ml when reconstituted with 100 µl of deionized water
    Purity SDS-PAGE > 90 %
    Type Recombinant Antigens
    Description Recombinant human S100 calcium binding protein A9 antigen is produced by E.coli expression system and the target gene encoding Thr2-Pro114 is expressed. Predicted molecular weight: 13 kDa.
    Product code 710037
    Shelf life and storage -20 °C
    Product concentration 0.5 mg/ml when reconstituted with 1000 µl of deionized water     
    Purity SDS-PAGE > 90 %    
    Type Recombinant Antigens
    Description Recombinant human S100 calcium binding protein A9 antigen is produced by E.coli expression system and the target gene encoding Thr2-Pro114 is expressed. Predicted molecular weight: 13 kDa.
    Product code 710036
    Shelf life and storage -20 °C
    Product concentration 0.5 mg/ml when reconstituted with 2000 µl of deionized water     
    Purity SDS-PAGE > 90 %         

IL-6

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human interleukin-6 (IL-6)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100328
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 – 7.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.0 x 105 1/Ms
    Dissociation rate constant 5.6 x 10-5 1/s
    Affinity constant KA = 1.8 x 109 1/M; KD = 5.6 x 10-10 M (=0.56 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human interleukin-6 (IL-6)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100329
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 18 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 – 7.5
    Purity ≥ 95 %
    Subclass IgG2b
    Association rate constant 1.9 x 105 1/Ms
    Dissociation rate constant 1.7 x 10-4 1/s
    Affinity constant KA = 1.1 x 109 1/M; KD = 9.2 x 10-10 M (=0.92 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human interleukin-6 (IL-6)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100330
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.0 - 7.9
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant 3.6 x 104 1/Ms
    Dissociation rate constant 1.5 x 10-5 1/s
    Affinity constant KA = 2.5 x 109 1/M; KD = 4.1 x 10-10 M (=0.41 nM)

Recombinant Antigens

IL-8

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human interleukin-8
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100218
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 – 7.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 3 x 105 1/Ms
    Dissociation rate constant 2 x 10-3 1/s
    Affinity constant KA = 2 x 108 1/M ; KD = 5 x 10-9 M

Lactoferrin

Recombinant Antigens

    Type Recombinant Antigens
    Description Recombinant human lactoferrin, also known as lactotransferrin/LTF antigen is produced by mammalian expression system and the target gene encoding Gly20-Lys710 is expressed with a 6His tag at the C-terminus. Predicted molecular weight: 77 kDa.
    Product code 710016
    Product concentration 0.5 mg/ml
    Type Recombinant Antigens
    Description Recombinant human lactoferrin, also known as lactotransferrin/LTF, antigen is produced by mammalian expression system and the target gene encoding Gly20-Lys710 is expressed with a 6His tag at the C-terminus. Predicted molecular weigh: 77 kDa.
    Product code 710041
    Shelf life and storage -20 °C
    Product concentration 0.5 mg/ml when reconstituted with 1000 µl of deionized water
    Type Recombinant Antigens
    Description Recombinant human lactoferrin, also known as lactotransferrin/LTF, antigen is produced by mammalian expression system and the target gene encoding Gly20-Lys710 is expressed with a 6His tag at the C-terminus. Predicted molecular weight: 77 kDa.
    Product code 710040
    Shelf life and storage -20 °C
    Product concentration 0.5 mg/ml when reconstituted with 2000 µl of deionized water

NGAL

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neutrophil gelatinase-associated lipocalin (NGAL)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100579
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.7 – 6.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neutrophil gelatinase-associated lipocalin (NGAL)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100580
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.9 – 6.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neutrophil gelatinase-associated lipocalin (NGAL)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100581
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.8 – 6.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neutrophil gelatinase-associated lipocalin (NGAL)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100582
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.7 – 6.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D

PCT

PCT leaflet

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Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human calcitonin and procalcitonin
    Description Monoclonal antibody raised against human calcitonin. In vitro cultured mouse hybridomas.
    Product code 700020
    Product buffer solution 0.1 M BBS, pH 8, 0.9 % NaCl
    Shelf life and storage 60 months from manufacturing at 2–8 °C
    Product concentration > 1.0 mg/ml
    Immunoreactivity Not Determined (N/D)
    IEF profile 6.0 - 6.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human procalcitonin (PCT)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100561
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.1 – 7.1
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human procalcitonin (PCT)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100565
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 - 6.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human procalcitonin (PCT)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100562
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.4 – 6.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 4.8 x 104 1/Ms     
    Dissociation rate constant 2.2 x 10-4 1/s 
    Affinity constant KA = 2.2 x 108 1/M; KD = 4.6 x 10-9 M (=4.6 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human procalcitonin (PCT)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100563
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 2.5 x 104 1/Ms
    Dissociation rate constant Does not dissociate under conditions used
    Affinity constant Not Applicable (N/A)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human procalcitonin (PCT)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100564
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.0 - 6.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 2.9 x 104 1/Ms
    Dissociation rate constant Does not dissociate under conditions used
    Affinity constant Not Applicable (N/A)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human procalcitonin (PCT)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100567
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 – 7.4
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 6.7 x 104 1/Ms
    Dissociation rate constant 3.5 x 10-4 1/s
    Affinity constant KA = 1.9 x 108 1/M; KD = 5.2 x 10-9 M (=5.2 nM)

Recombinant Antigens

Serum Amyloid A

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human serum amyloid A (SAA)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100279
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 18 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.5 – 8.7
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant 1.9 x 105 1/Ms
    Dissociation rate constant 1.8 x 10-4 1/s
    Affinity constant KA = 1.0 x 109 1/M; KD = 9.6 x 10-10
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human serum amyloid A (SAA)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100289
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 18 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.8 – 7.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.1 x 105 1/Ms
    Dissociation rate constant 3.0 x 10-4 1/s
    Affinity constant KA = 3.5 x 108 1/M; KD = 2.8 x 10-9 M (= 2.8 nM)

Recombinant Antigens

Transferrin

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human transferrin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100525
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.7 – 7.4
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 0.6 x 106 1/Ms
    Dissociation rate constant 1.7 x 10-4 1/s
    Affinity constant KA = 3.8 x 109 1/M; KD = 2.6 x 10-10 M (=0.26 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human transferrin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100440
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 - 7.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 6.7 x 106 1/Ms
    Dissociation rate constant 1.3 x 10-5 1/s
    Affinity constant KA = 5.3 x 1011 1/M; KD = 1.9 x 10-12 M (=0.002 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human transferrin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100474
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.4 – 8.7
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant 2.2 x 106 1/Ms
    Dissociation rate constant 1.1 x 10-4 1/s
    Affinity constant KA = 2.1 x 1010 1/M; KD = 4.8 x 10-11 M (=0.048 nM)

Trypsinogen-2

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human trypsinogen-2
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100107
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °CAnalyte descriptionTrypsinogen is the precursor form of the pancreatic enzyme trypsin. It is found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen. It is activated by enteropeptidase, which is found in the intestinal mucosa, to form trypsin. Once activated, the trypsin can activate more trypsinogen into trypsin. Trypsin cleaves peptide bond on carboxyl side of basic amino acids. High serum trypsinogen levels are seen in acute pancreatitis, and cystic fibrosis. Determination of urine trypsinogen-2 is also a useful test to detect acute pancreatitis and to evaluate disease severity.
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 – 7.6
    Purity ≥ 95 %
    Subclass IgG2b
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 1.4 x 108 l/mol
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human trypsinogen-2
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100108
    Product buffer solution 50 mM Na-citrate, pH 7.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.0 – 6.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 1.6 x 108 l/mol

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