MedixMAB™ antibodies & MedixAntigens™

Kidney markers

Cystatin C

Cystatin C is an emerging renal biomarker. It is used for the diagnosis of chronic kidney disease. Cystatin C has also been associated with an increased risk of cardiovascular disease and heart failure.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human Cystatin C
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100702
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 - 7.1
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human Cystatin C
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100690
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.2 - 7.3
    Purity ≥ 95 %
    Subclass IgG2b
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human Cystatin C
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100703
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.2 - 6.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human Cystatin C
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100689
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.8 - 6.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human Cystatin C
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100659
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.4 - 6.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D

Recombinant Antigens

KIM-1

Kidney injury molecule 1 (KIM-1) also known as T-cell immunoglobulin mucin receptor 1 (TIM-1) or Hepatitis A virus cellular receptor 1 (HAVcr-1), is released from renal tubular cells after injury. It can be used in the diagnosis of acute kidney injury (AKI).

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human kidney injury molecule 1
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100738
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.2 - 6.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human kidney injury molecule 1
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100739
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 - 7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human kidney injury molecule 1
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100740
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 - 7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human kidney injury molecule 1
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100742
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 - 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D

NGAL

Neutrophil gelatinase-associated lipocalin (NGAL) also known as lipocalin-2, is used as a biomarker of kidney injury, and has also been shown to play a role in cancer and cardiovascular events.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neutrophil gelatinase-associated lipocalin (NGAL)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100579
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.8 - 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 6.4 x 105 1/Ms
    Dissociation rate constant 4.0 x 10-4 1/s
    Affinity constant KA = 1.6 x 109 1/M; KD = 6.3 x 10-10 M (= 0.63 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neutrophil gelatinase-associated lipocalin (NGAL)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100580
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 - 7.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 2.2 x 105 1/Ms
    Dissociation rate constant Does not dissosiate under conditions used
    Affinity constant Not Applicable (N/A)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neutrophil gelatinase-associated lipocalin (NGAL)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100581
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.8 – 6.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.8 x 105 1/Ms
    Dissociation rate constant 3.4 x 10-5 1/s
    Affinity constant KA = 5.3 x 109 1/M; KD = 1.8 x 10-10 M (= 0.18 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neutrophil gelatinase-associated lipocalin (NGAL)
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100582
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.0 – 7.1
    Purity ≥ 95 %
    Subclass IgG1Association rate rconstant5.6 x 104 1/Ms
    Association rate constant Not Determined (N/D)
    Dissociation rate constant 4.9 x 10-5 1/s
    Affinity constant KA = 1.2 x 109 1/M; KD = 8.6 x 10-10 M (= 0.86 nM)

Recombinant Antigens

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