MedixMAB™ antibodies & MedixAntigens™

Neurology

NSE

Neuron-specific enolase (NSE) has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrinetumors, and melanoma.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neuron-specific enolase, -isoform
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100388
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6–7.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant KA = 4.3 x 108 1/M
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human neuron-specific enolase, -isoform
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100408
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.2–8.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant KA = 2.2 x 108 1/M

Recombinant Antigens

S100B

S100B belongs to the family of dimeric calcium-binding S100 proteins. S100B is a biomarker for traumatic brain injury.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human S100B
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100778
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6–7.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human S100B
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100779
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.0–7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human S100B
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
    Product code 100781
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage Unspecified, storage at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.8–7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D

Recombinant Antigens

    Type Recombinant Antigens
    Description Recombinant human S100 calcium binding protein B antigen is produced by E. coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the N-terminus. Predicted molecular weight: 12 kDa.
    Product code 710014
    Product buffer solution 20 mM PBS, pH 7.4, 150 mM NaCl
    Shelf life and storage -20 °C
    Product concentration 0.5 mg/ml when reconstituted with 100 µl of deionized water
    Purity SDS-PAGE > 90 %
    Type Recombinant Antigens
    Description Recombinant human S100 calcium binding protein B antigen is produced by E. coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the N-terminus. Predicted molecular weight: 12 kDa.
    Product code 710045
    Product buffer solution 20 mM PBS, pH 7.4, 150 mM NaCl
    Shelf life and storage -20 °C
    Product concentration 0.5 mg/ml when reconstituted with 1000 µl of deionized water
    Purity SDS-PAGE > 90 %
    Type Recombinant Antigens
    Description Recombinant human S100 calcium binding protein B antigen is produced by E. coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the N-terminus. Predicted molecular weight: 12 kDa.
    Product code 710044
    Product buffer solution 20 mM PBS, pH 7.4, 150 mM NaCl
    Shelf life and storage -20 °C
    Product concentration 0.5 mg/ml when reconstituted with 2000 µl of deionized water
    Purity SDS-PAGE > 90 %

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