MedixMAB™ antibodies & MedixAntigens™
Neurology
NSE
Neuron-specific enolase (NSE) has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrinetumors, and melanoma.
Monoclonal Antibodies
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human neuron-specific enolase, -isoform |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code | 100388 |
| Product buffer solution | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | 36 months from manufacturing at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 6.6–7.7 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | KA = 4.3 x 108 1/M |
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human neuron-specific enolase, -isoform |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code | 100408 |
| Product buffer solution | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | 24 months from manufacturing at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 7.2–8.0 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | KA = 2.2 x 108 1/M |
Recombinant Antigens
| Type | Recombinant Antigens |
|---|---|
| Description | Recombinant human neuron-specific enolase (NSE) γ-isoform with a C-terminal histidine tag. Predicted molecular weight: 48 kDa. |
| Product code | 610150 |
| Product buffer solution | 50 mM Tris-HCl, 150 mM NaCl, 5 mM MgSO4, 0.02 % Tween 20, pH 7.5, 0.095 % NaN3 as a preservative |
| Shelf life and storage | Unspecified, storage at 2–8 °C |
| Product concentration | 0.5 mg/ml |
S100B
S100B belongs to the family of dimeric calcium-binding S100 proteins. S100B is a biomarker for traumatic brain injury.
Monoclonal Antibodies
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human S100B |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100778 |
| Product buffer solution | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | Unspecified, storage at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 6.6–7.9 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | N/D |
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human S100B |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100779 |
| Product buffer solution | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | Unspecified, storage at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 7.0–7.5 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | N/D |
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human S100B |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100781 |
| Product buffer solution | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | Unspecified, storage at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 6.8–7.2 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | N/D |
Recombinant Antigens
| Type | Recombinant Antigens |
|---|---|
| Description | Recombinant human S100 calcium binding protein B antigen is produced by E. coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the N-terminus. Predicted molecular weight: 12 kDa. |
| Product code | 710014 |
| Product buffer solution | 20 mM PBS, pH 7.4, 150 mM NaCl |
| Shelf life and storage | -20 °C |
| Product concentration | 0.5 mg/ml when reconstituted with 100 µl of deionized water |
| Purity | SDS-PAGE > 90 % |
| Type | Recombinant Antigens |
|---|---|
| Description | Recombinant human S100 calcium binding protein B antigen is produced by E. coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the N-terminus. Predicted molecular weight: 12 kDa. |
| Product code | 710045 |
| Product buffer solution | 20 mM PBS, pH 7.4, 150 mM NaCl |
| Shelf life and storage | -20 °C |
| Product concentration | 0.5 mg/ml when reconstituted with 1000 µl of deionized water |
| Purity | SDS-PAGE > 90 % |
| Type | Recombinant Antigens |
|---|---|
| Description | Recombinant human S100 calcium binding protein B antigen is produced by E. coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the N-terminus. Predicted molecular weight: 12 kDa. |
| Product code | 710044 |
| Product buffer solution | 20 mM PBS, pH 7.4, 150 mM NaCl |
| Shelf life and storage | -20 °C |
| Product concentration | 0.5 mg/ml when reconstituted with 2000 µl of deionized water |
| Purity | SDS-PAGE > 90 % |
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