MedixMAB™ antibodies & MedixAntigens™
Serology
IgA
Immunoglobulin A (IgA) is an antibody which plays a critical role in mucosal immunity. IgA has two subclasses (IgA1 and IgA2) and can exist in a dimeric form called secretory IgA (sIgA).
Monoclonal Antibodies
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human immunoglobulin A |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100101 |
| Product buffer solution | 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | 36 months from manufacturing at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 6.6–7.7 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | KA = 3 x 109 1/M |
IgE
Immunoglobulin E (IgE) plays an important role in allergy and defence against parasites. IgE is a class of antibody that has only been found in mammals.
Monoclonal Antibodies
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human immunoglobulin E |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100429 |
| Product buffer solution | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | 24 months from manufacturing at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 5.8–7.0 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | KA = 8 x 109 1/M |
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human immunoglobulin E |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100858 |
| Product buffer solution | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | 24 months from manufacturing at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 6.1–7.1 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | KA = 9.2 x 109 1/M |
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human immunoglobulin E |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100106 |
| Product buffer solution | 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 25 % ethylene glycol, 0.095 % NaN3 as a preservative |
| Shelf life and storage | 36 months from manufacturing at 2–8 °C |
| Product concentration | 1.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 6.3–7.8 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | KA = 1.2 x 1010 1/M |
IgG
Immunoglobulin G (IgG) antibodies are involved in the secondary immune response. IgG is a monomeric immunoglobulin consisting of four subclasses and constituting 75% of serum immunoglobulins in humans.
Monoclonal Antibodies
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human immunoglobulin G |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100087 |
| Product buffer solution | 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | 36 months from manufacturing at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 6.7–7.8 |
| Purity | ≥ 95 % |
| Subclass | IgG2a |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | KA = 2 x 1010 1/M |
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human immunoglobulin G |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100152 |
| Product buffer solution | 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | 36 months from manufacturing at 2–8 °C |
| Product concentration | > 10.0 mg/ml |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 6.7–7.8 |
| Purity | ≥ 95 % |
| Subclass | IgG2a |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | KA = 2 x 1010 1/M |
IgM
Immunoglobulin M (IgM) is involved in primary immune response. IgM is a basic antibody that first appears in response to antigen exposure and indicates recent infection in patient’s serum.
Monoclonal Antibodies
| Type | Monoclonal Antibodies |
|---|---|
| Specificity | Antibody recognizes human immunoglobulin M |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Product code | 100084 |
| Product buffer solution | 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage | 36 months from manufacturing at 2–8 °C |
| Product concentration | 5.0 mg/ml (+/- 10 %) |
| Immunoreactivity | 80–120 % compared to the reference sample in an FIA test |
| IEF profile | 6.1–7.0 |
| Purity | ≥ 95 % |
| Subclass | IgG1 |
| Association rate constant | Not Determined (N/D) |
| Dissociation rate constant | N/D |
| Affinity constant | KA = 6 x 1010 1/M |
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