MedixMAB™ antibodies & MedixAntigens™

Serology

IgA

Immunoglobulin A (IgA) is an antibody which plays a critical role in mucosal immunity. IgA has two subclasses (IgA1 and IgA2) and can exist in a dimeric form called secretory IgA (sIgA).

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human immunoglobulin A
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100101
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.8 – 7.7
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 3 x 109 l/mol

IgE

Immunoglobulin E (IgE) plays an important role in allergy and defence against parasites. IgE is a class of antibody that has only been found in mammals.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human immunoglobulin E
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100429
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.8 – 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 8 x 109 l/mol
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human immunoglobulin E
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100105
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.5 – 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 9.2 x 109 l/mol
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human immunoglobulin E
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100106
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 25 % ethylene glycol, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 – 7.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 1.2 x 1010 l/mol

IgG

Immunoglobulin G (IgG) antibodies are involved in the secondary immune response. IgG is a monomeric immunoglobulin consisting of four subclasses and constituting 75% of serum immunoglobulins in humans.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human immunoglobulin G
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100087
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.7 – 7.8
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 2 x 1010 l/mol
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human immunoglobulin G
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100152
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration > 10.0 mg/ml
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.7 – 7.8
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 2 x 1010 l/mol

IgM

Immunoglobulin M (IgM) is involved in primary immune response. IgM is a basic antibody that first appears in response to antigen exposure and indicates recent infection in patient’s serum.

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human immunoglobulin M
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100084
    Product buffer solution 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.1 – 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 6 x 1010 l/mol

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