MedixMAB™ antibodies & MedixAntigens™

Thyroid Markers

Thyroglobulin

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyroglobulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100331
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 18 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.0 – 8.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 8.6 x 103 1/Ms
    Dissociation rate constant 1.2 x 10-5 1/s
    Affinity constant KA = 7.3 x 108 1/M; KD = 1.4 x 10-9 M (=1.4 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyroglobulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100332
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.9 – 8.0
    Purity ≥ 95 %
    Subclass IgG2b
    Association rate constant 1.7 x 105 1/Ms
    Dissociation rate constant 3.7 x 10-5 1/s
    Affinity constant KA = 4.5 x 109 1/M; KD = 2.2 x 10-10 M (=0.22 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyroglobulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100333
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.8 – 7.5
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 7.2 x 104 1/Ms
    Dissociation rate constant 7.9 x 10-4 1/s
    Affinity constant KA = 9.1 x 107 1/M; KD = 1.1 x 10-8 M (=11 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyroglobulin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100334
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.8 – 8.8
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 6.2 x 105 1/Ms
    Dissociation rate constant 1.3 x 10-5 1/s
    Affinity constant KA = 4.8 x 1010 1/M; KD = 2.1 x 10-11 M (=0.02 nM)

TSH

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyrotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100023
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 12 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.0 – 7.6
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 3.6 x 105 1/Ms
    Dissociation rate constant 7.0 x 10-5
    Affinity constant KA = 5.1 x 109 1/M; KD = 2.0 x 10-10 M (= 0.20 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyrotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100026
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 – 7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 8.5 x 105 1/Ms
    Dissociation rate constant 3.9 x 10-5 1/s
    Affinity constant KA = 2.2 x 1010 1/M; KD = 4.6 x 10-11 M (= 0.05 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyrotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100030
    Product buffer solution 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.3 – 6.9
    Purity ≥ 95 %
    Subclass IgG2a
    Association rate constant 1.2 x 106 1/Ms
    Dissociation rate constant 1.9 x 10-4
    Affinity constant KA = 6.6 x 109 1/M; KD = 1.5 x 10-10 M (= 0.15 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyrotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100254
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 24 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.6 – 7.0
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 1.1 x 106 1/Ms
    Dissociation rate constant 2.0 x 10-4
    Affinity constant KA = 5.4 x 109 1/M; KD = 1.8 x 10-10 M (= 0.18 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyrotropin and its free beta subunit
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100033
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 1.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 6.6 – 7.3
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 9.6 x 105 1/Ms
    Dissociation rate constant 3.8 x 10-5
    Affinity constant KA = 2.5 x 1010 1/M; KD = 4.0 x 10-11 M (= 0.04 nM)
    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyrotropin
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100034
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 25 % ethylene glycol, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 5.8 – 7.2
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant 2.1 x 106 1/Ms
    Dissociation rate constant 1.0 x 10-4 1/s
    Affinity constant KA = 2.1 x 1010 1/M; KD = 4.8 x 10-11 M (= 0.05 nM)

T4

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human thyroxine
    Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
    Product code 100348
    Product buffer solution 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
    Shelf life and storage 36 months from manufacturing at 2–8 °C
    Product concentration 5.0 mg/ml (+/- 10 %)
    Immunoreactivity 80–120 % compared to the reference sample in an FIA test
    IEF profile 7.0 – 7.9
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant 1 x 1010 l/mol

Triiodothyronine

Monoclonal Antibodies

    Type Monoclonal Antibodies
    Specificity Antibody recognizes human triiodothyronine (T3)
    Description Monoclonal antibody raised against human T3. In vitro cultured mouse hybridomas.
    Product code 700015
    Product buffer solution 0.1 M PBS, pH 7.4, 0.9 % NaCI, 0.05 % NaN3 as a preservative
    Shelf life and storage 60 months from manufacturing at 2–8 °C
    Product concentration > 1.0 mg/ml
    Immunoreactivity Passed in ELISA when Anti-h T3 antibody 10550 was used as a capture antibody
    IEF profile 6.7 - 7.1
    Purity ≥ 95 %
    Subclass IgG1
    Association rate constant Not Determined (N/D)
    Dissociation rate constant N/D
    Affinity constant N/D

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