MedixMAB™ antibodies & MedixAntigens™
Tumor Markers
For both diagnostic and therapeutic purposes, cancer markers are being monitored to get an idea about the status of the disease. However, most individual cancer markers are not highly specific, because they are not exclusively expressed and secreted by tumour cells. Therefore, instead of the mere presence of one marker, specificity is often obtained by measuring the levels of a combination of different markers or different forms of the same marker.
AFP
Alpha-fetoprotein (AFP) is a major plasma protein produced by the fetus. AFP is measured in pregnancy as a screening test for a subset of developmental abnormalities. It is also used as a biomarker to detect a subset of tumors.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human Alpha1-fetoprotein
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100014
|
| Product buffer solution |
0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
24 months from manufacturing at 2–8 °C
|
| Product concentration |
1.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.5 - 7.2
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
4 x 1010 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human Alpha1-fetoprotein
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100015 |
| Product buffer solution |
0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
24 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.5 – 7.1
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
3 x 1010 l/mol
|
Calcitonin
Calcitonin is a peptide hormone secreted by the thyroid gland. Calcitonin concentrations are increased in patients with medullary thyroid carcinoma (MTC) and can be used to diagnose and monitor the disease.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human calcitonin |
| Description |
Monoclonal antibody raised against human calcitonin. In vitro cultured mouse hybridomas. |
| Product code |
700019 |
| Product buffer solution |
0.1 M BBS, pH 8, 0.9 % NaCl |
| Shelf life and storage |
60 months from manufacturing at 2–8 °C |
| Product concentration |
> 1.0 mg/ml |
| Immunoreactivity |
Passed in ELISA when Anti-h Calcitonin antibody 4050 was used as a detection antibody |
| IEF profile |
6.3 - 7.3 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human calcitonin and procalcitonin
|
| Description |
Monoclonal antibody raised against human calcitonin. In vitro cultured mouse hybridomas.
|
| Product code |
700020
|
| Product buffer solution |
0.1 M BBS, pH 8, 0.9 % NaCl
|
| Shelf life and storage |
60 months from manufacturing at 2–8 °C
|
| Product concentration |
> 1.0 mg/ml
|
| Immunoreactivity |
Not Determined (N/D)
|
| IEF profile |
6.0 - 6.3
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
N/D
|
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human procalcitonin (PCT)
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100563
|
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
12 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.2 - 6.9
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
2.5 x 104 1/Ms
|
| Dissociation rate constant |
Does not dissociate under conditions used
|
| Affinity constant |
Not Applicable (N/A)
|
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human procalcitonin (PCT)
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100564
|
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
24 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.0 - 6.9
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
2.9 x 104 1/Ms
|
| Dissociation rate constant |
Does not dissociate under conditions used
|
| Affinity constant |
Not Applicable (N/A)
|
|
|
CA15-3
Cancer antigen 15-3 (CA15-3) is identified through the use of two monoclonal antibodies, one specific for the MUC-1 protein core and another specific for a
carbohydrate epitope on the MUC-1 protein. CA15-3 is a widely used serum marker for breast cancer monitoring.
Antibodies 4401, 4402, 4403, and 4404 recognize the MUC-1 core protein of CA15-3.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes MUC-1core protein of cancer antigen 15-3 |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100591 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
Unspecified, storage at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.4 – 6.6 |
| Purity |
≥ 95 % |
| Subclass |
IgG1, light chain |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes MUC-1core protein of cancer antigen 15-3 |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100595 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
Unspecified, storage at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.6 – 6.7 |
| Purity |
≥ 95 % |
| Subclass |
IgG1, light chain |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes MUC-1core protein of cancer antigen 15-3 |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100583 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
Unspecified, storage at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.2 – 6.4 |
| Purity |
≥ 95 % |
| Subclass |
IgG1, light chain |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes MUC-1core protein of cancer antigen 15-3
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100584
|
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
12 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
5.9 - 7.1
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1, light chain
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
N/D
|
|
|
CA125
Cancer antigen 125 (CA125) is a peptide epitope on the mucin glycoprotein MUC16. CA125 is the most widely used serum biomarker to monitor epithelial ovarian cancer. It is also used for the differential diagnosis of pelvic masses.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human cancer antigen 125 (CA125) |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100598 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
12 months from manufacturing at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.4 - 7.2 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human cancer antigen 125 (CA125) |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100628 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
12 months from manufacturing at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.3 - 7.3 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
CA19-9
Carbohydrate antigen 19-9 (CA19-9) is a tumor biomarker also called Sialyl Lewis
A. Serum level measurements of CA19-9 are widely used in pancreatic cancer patients for monitoring their response to cancer treatments.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes carbohydrate antigen 19-9 (CA19-9)
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100609
|
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
18 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
7.5 – 8.8
|
| Purity |
≥ 95 %
|
| Subclass |
IgG3
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
N/D
|
|
|
CEA
Carcinoembryonic antigen (CEA) is normally produced during fetal development. It has been used as a tumor marker for colorectal cancer and several carcinomas.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human carcinoembryonic antigen
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100044 |
| Product buffer solution |
0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
1.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.1 – 7.2
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
5 x 1010 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human carcinoembryonic antigen
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100428 |
| Product buffer solution |
0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.0 – 7.1
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
3 x 1010 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human carcinoembryonic antigen
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100047 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
5.7 – 7.1
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
1 x 1011 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human carcinoembryonic antigen
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100048 |
| Product buffer solution |
0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
24 months from manufacturing at 2–8 °C
|
| Product concentration |
1.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.5 – 7.5
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
1.5 x 1010 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human carcinoembryonic antigen
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100049 |
| Product buffer solution |
0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
1.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.8 – 7.6
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
4 x 109 l/mol
|
CYFRA21-1
CYFRA 21-1 is a fragment of Cytokeratin 19. Serum CYFRA 21-1 has been used as a tumor marker, especially in non-small cell lung cancer.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human cytokeratin 19 CYFRA21-1 fragment
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100220 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.05 % Sulfobetaine, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
6 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.5 – 7.1
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
N/D
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human CYFRA21-1 fragment of cytokeratin 19 |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100221 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.05 % Sulfobetaine, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
12 months from manufacturing at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.9 – 8.6 |
| Purity |
≥ 95 % |
| Subclass |
IgG2a |
| Association rate constant |
1 x 104 1/Ms |
| Dissociation rate constant |
4 x 10-5 1/s |
| Affinity constant |
KA = 3 x 108 1/M, KD = 4 x 10-9 M |
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human CYFRA21-1 fragment of cytokeratin 19
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100222
|
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
12 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.5 - 8.1
|
| Purity |
≥ 95 %
|
| Subclass |
IgG2a
|
| Association rate constant |
3 x 104 1/Ms
|
| Dissociation rate constant |
6 x 10-5 1/s
|
| Affinity constant |
KA = 5 x 108 1/M, KD = 2 x 10-9 M
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human CYFRA21-1 fragment of cytokeratin 19 |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100223 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
12 months from manufacturing at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.7 – 7.4 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
5 x 104 1/Ms |
| Dissociation rate constant |
6 x 10-5 1/s |
| Affinity constant |
KA = 8 x 108 1/M, KD = 1 x 10-9 M |
Hemoglobin
Hemoglobin (Hb) is the iron-containing oxygen-transport metalloprotein in red blood cells. Hemoglobin carries oxygen from the lungs to the rest of the body. Deviation from normal values usually indicates abnormalities, such as anemia.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human hemoglobin (A0 and A1 equally well, A2 with lower affinity, and As with very low affinity)
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100079 |
| Product buffer solution |
37 mM citrate, 125 mM phosphate, pH 6.0, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.2 – 6.7
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
1 x 1010 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human hemoglobin (A0, A1 and AS equally well, A2 with low affinity)
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100080 |
| Product buffer solution |
0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.1 – 6.8
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
6 x 108 l/mol
|
HE4
Human epididymis protein 4 (HE4) is also known as WAP four-disulfide core
domain protein 2, and is a 124 amino acid long protease inhibitor. Serum HE4 is often measured together with CA125 to monitor progression of epithelial ovarian cancer after treatment.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human epididymis protein 4 (HE4) |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100593 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
Unspecified, storage at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.3 – 6.8 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not Determined (N/D) |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human epididymis protein 4 (HE4) |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100594 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
Unspecified, storage at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.2 – 6.9 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human epididymis protein 4 (HE4) |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100589 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
Unspecified, storage at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.5 – 7.2 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human epididymis protein 4 (HE4) |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100592 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
Unspecified, storage at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.5 – 7.2 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human epididymis protein 4 (HE4) |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100608 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
Unspecified, storage at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.6 – 7.0 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
Inhibin A
Inhibin alpha binds to either beta A or beta B subunit, to form inhibin A, or inhibin B, respectively. Inhibin A tests can be used in the diagnostics of Down syndrome.
Inhibin B is a marker of male infertility.
Inhibin beta A can form dimers with itself, with inhibin alpha, or inhibin beta B. The dimerization product with inhibin alpha subunit is called inhibin A. Assessment of inhibin A concentration is used in prenatal screening for Down syndrome.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human inhibin alpha subunit |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100711 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
12 months from manufacturing at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.3 - 7.2 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human inhibin beta A subunit, also known as activin beta A. |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100709 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
12 months from manufacturing at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
7.1 - 8.5 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not Determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
N/D |
|
|
NSE
Neuron-specific enolase (NSE) has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer,
carcinoid tumors, pancreatic endocrinetumors, and melanoma.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human neuron-specific enolase, -isoform
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100388 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.9 – 7.7
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
4.3 x 108 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human neuron-specific enolase, -isoform
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100408 |
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
24 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
7.2 – 8.0
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
2.2 x 108 l/mol
|
Pepsinogen I
Pepsinogen (PG I & II) is the pro-form of pepsin. It is produced in the stomach and secreted into the gastric lumen, but a small amount is also released into the blood. Alterations in the serum pepsinogen concentration may indicate gastric abnormalities.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human pepsinogen I
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100120
|
| Product buffer solution |
37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.5 – 7.3
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
4 x 1010 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human pepsinogen I
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100093
|
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
1.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.7 – 7.5
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
2 x 1010 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human pepsinogen I
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100143
|
| Product buffer solution |
37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.3 – 7.3
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
4 x 1010 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human pepsinogen I
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100095
|
| Product buffer solution |
37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
1.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
5.2 – 8.2
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
3 x 1010 l/mol
|
Recombinant Antigens
| Type |
Recombinant Antigens |
| Description |
Recombinant human pepsinogen I protein. Predicted molecular weight: 40 kDa.
|
| Product code |
610000
|
| Shelf life and storage |
Shelf life unspecified, storage at 2-8 °C
|
| Product concentration |
0.5 mg/ml when reconstituted with 200 µl of deionized water
|
| Purity |
SDS-PAGE
|
Pepsinogen II
Pepsinogen (PG I & II) is the pro-form of pepsin. It is produced in the stomach and secreted into the gastric lumen, but a small amount is also released into the blood. Alterations in the serum pepsinogen concentration may indicate gastric abnormalities.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human pepsinogen II
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100097
|
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.4 – 7.2
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
3 x 101o l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human pepsinogen II
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100098
|
| Product buffer solution |
37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
24 months from manufacturing at 2–8 °C
|
| Product concentration |
1.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.2 – 8.0
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
1 x 109 l/mol
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human pepsinogen II
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100121
|
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
24 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.4 – 7.7
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not Determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
3.5 x 109 l/mol
|
Recombinant Antigens
| Type |
Recombinant Antigens |
| Description |
Recombinant human pepsinogen II protein. Predicted molecular weight: 41 kDa.
|
| Product code |
610001
|
| Shelf life and storage |
Shelf life unspecified, storage at 2-8 °C
|
| Product concentration |
0.5 mg/ml when reconstituted with 200 µl of deionized water
|
| Purity |
SDS-PAGE
|
PSA
Prostate-specific antigen (PSA) is a protein produced by the cells of the prostate gland. PSA is often elevated in the presence of prostate cancer and in other prostate disorders. Free PSA is a form of PSA that does not become attached to other blood proteins. Decreased levels of free PSA may indicate prostate cancer.
Monoclonal Antibodies
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human prostate-specific antigen |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100102 |
| Product buffer solution |
37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
36 months from manufacturing at 2–8 °C |
| Product concentration |
5.0 mg/ml (+/- 10 %) |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
6.5 – 7.2 |
| Purity |
≥ 95 % |
| Subclass |
IgG1 |
| Association rate constant |
Not determined (N/D) |
| Dissociation rate constant |
N/D |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human prostate-specific antigen |
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components |
| Product code |
100103 |
| Product buffer solution |
37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Shelf life and storage |
36 months from manufacturing at 2–8 °C |
| Product concentration |
1.0 – 1.1 mg/ml |
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test |
| IEF profile |
7.0 – 7.4 |
| Purity |
≥ 95 % |
| Subclass |
IgG2a |
| Association rate constant |
Not determined (N/D) |
| Dissociation rate constant |
N/D |
| Affinity constant |
1 x 1010 l/mol |
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human prostate-specific antigen
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100139
|
| Product buffer solution |
37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
36 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
6.3 - 7.0
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
Not determined (N/D)
|
| Dissociation rate constant |
N/D
|
| Affinity constant |
3 x 109 l/mol
|
|
|
| Type |
Monoclonal Antibodies |
| Specificity |
Antibody recognizes human free prostate-specific antigen
|
| Description |
Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components
|
| Product code |
100488
|
| Product buffer solution |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
|
| Shelf life and storage |
18 months from manufacturing at 2–8 °C
|
| Product concentration |
5.0 mg/ml (+/- 10 %)
|
| Immunoreactivity |
80–120 % compared to the reference sample in an FIA test
|
| IEF profile |
5.7 – 6.9
|
| Purity |
≥ 95 %
|
| Subclass |
IgG1
|
| Association rate constant |
2.0 x 106 1/Ms
|
| Dissociation rate constant |
1.5 x 10-5 1/s
|
| Affinity constant |
KA = 1.3 x 1011 1/M; KD = 7.5 x 10-12 M (=0.0075 nM)
|
S100B
S100B belongs to the family of dimeric calciumbinding S100 proteins. S100B is a biomarker for traumatic brain injury.
Recombinant Antigens
| Type |
Recombinant Antigens |
| Description |
Recombinant human S100 calcium binding protein B antigen is produced by E.coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the N-terminus. Predicted molecular weight: 12 kDa. |
| Product code |
710014 |
| Shelf life and storage |
-20 °C |
| Product concentration |
0.5 mg/ml when reconstituted with 100 µl of deionized water |
|
|
| Type |
Recombinant Antigens |
| Description |
Recombinant human S100 calcium binding protein B antigen is produced by E.coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the N-terminus. Predicted molecular weight: 12 kDa.
|
| Product code |
710045
|
| Shelf life and storage |
-20 °C
|
| Product concentration |
0.5 mg/ml when reconstituted with 1000 µl of deionized water
|
|
|
| Type |
Recombinant Antigens |
| Description |
Recombinant human S100 calcium binding protein B antigen is produced by E.coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the N-terminus. Predicted molecular weight: 12 kDa.
|
| Product code |
710044
|
| Shelf life and storage |
-20 °C
|
| Product concentration |
0.5 mg/ml when reconstituted with 2000 µl of deionized water
|
|
|
