Anti-h IgM 7408 SPRN-5

Datasheet

Catalog Number: 100084

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Key Features

Form :

Liquid, may turn slightly opaque during storage

Species Reactivity :

Human

Application :

FIA

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Key Documents

Product Specification

Product Citations

Product Overview

Product Name	Anti-h IgM 7408 SPRN-5
Catalog Number	100084
Description	Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
Application	FIA
Alternative Names	(click to expand) Anti-human immunoglobulin M
Brand	Medix Biochemica

Further Specification

Form/Appearance	Liquid, may turn slightly opaque during storage
Concentration	5.0 mg/ml (+/- 10 %)
Isotype	IgG1
Clonality	Monoclonal
Epitope	Recognizes an epitope in the Fc region of IgM.
Purity	≥ 95 %
Affinity constant	KA = 6 x 10¹⁰ 1/M
Associated Products	Native IgM antigen Lee Biosolutions 340-31 and 340-35, and native IgM fc5µ antigen Lee Biosolutions 340-33
Buffer	37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
IEF Profile	6.1–7.0
Cross Reactivity	Human IgG < 0.01 %, Human IgA < 0.02 %, Goat IgG < 0.01 %, Rabbit IgG < 0.01 %, Equine IgG < 0.01 %, Porcine IgG < 0.02 %, Bovine IgG < 0.01 %, Ovine IgG < 0.01 %
Specificity	Antibody recognizes human immunoglobulin M

Storage and Shipping

Storage	+2-8°C
Shipping	Cold packs
Shelf Life	36 months

References

References	Hashida, S., Ishikawa, S., Hashinaka, K., Nishikata, I., Oka, S., and Ishikawa, E. (2000) Earlier detection of human immunodeficiency virus type 1 p24 antigen and immunoglobulin G and M antibodies to p17 antigen in seroconversion serum panels by immune complex transfer enzyme immunoassays. Clin. Diag. Lab. Immunol., 7(6):872-881. Juhela, S., Hyöty, H., Lönnrot, M., Roivainen, M., Simell, O., and Ilonen, J., (1998) Enterovirus infections and enterovirus specific T-cell responses in infancy. J. Med. Virol., 54:226-232. Juhela, S., Hyöty, H., Hinkkanen, A., Elliott, J., Roivainen, M., Kulmala, P., Rahko, J., Knip, M., and Ilonen, J., (1999) T cell responses to enterovirus antigens and to b-cell autoantigens in unaffected children positive for IDDM-associated autoantibodies. J. Autoimmun., 12:269-278. Hiltunen, M., Hyöty, H., Knip, M., Ilonen, J., Reijonen, H., Vähäsalo, P., Roivainen, R., Lönnrot, M., Leinikki, P., Hovi, T., Åkerblom, H.K., and the Childhood Diabetes in Finland Group (DiMe) study Group, (1997) Islet cell antibody seroconversion in chil¬dren is temporally associated with enterovirus infections. J. Inf. Dis., 175:554-560. Lönnrot, M., Knip, M., Roivianen, M., Koskela, P., Åkerblom, H.K., and Hyöty, H., (1998) Onset of type 1 diabetes mellitus in infancy after enterovirus infections. Diabetic Med., 15:431-434. Valtanen, S., Roivainen, M., and Hovi, T. (1999) Problems with biotin-labelled virions as probes in poliovirus-specific m-capture-IgM assays. J. Clin. Virol., 14:17-23. Viskari, H.R., Roivianen, M., Reunanen, A., Pitkäniemi, J., Sadeharju, K., Koskela, P., Hovi, T., Leinikki, P., Vilja, P., Tuomilehto, J., and Hyöty, H., (2002) Materal first-trimester enterovirus infection and future risk of type 1 diabetes in the exposed fetus. Diabet., 51:2568-2571.

Hashida, S., Ishikawa, S., Hashinaka, K., Nishikata, I., Oka, S., and Ishikawa, E. (2000) Earlier detection of human immunodeficiency virus type 1 p24 antigen and immunoglobulin G and M antibodies to p17 antigen in seroconversion serum panels by immune complex transfer enzyme immunoassays. Clin. Diag. Lab. Immunol., 7(6):872-881. Juhela, S., Hyöty, H., Lönnrot, M., Roivainen, M., Simell, O., and Ilonen, J., (1998) Enterovirus infections and enterovirus specific T-cell responses in infancy. J. Med. Virol., 54:226-232. Juhela, S., Hyöty, H., Hinkkanen, A., Elliott, J., Roivainen, M., Kulmala, P., Rahko, J., Knip, M., and Ilonen, J., (1999) T cell responses to enterovirus antigens and to b-cell autoantigens in unaffected children positive for IDDM-associated autoantibodies. J. Autoimmun., 12:269-278. Hiltunen, M., Hyöty, H., Knip, M., Ilonen, J., Reijonen, H., Vähäsalo, P., Roivainen, R., Lönnrot, M., Leinikki, P., Hovi, T., Åkerblom, H.K., and the Childhood Diabetes in Finland Group (DiMe) study Group, (1997) Islet cell antibody seroconversion in chil¬dren is temporally associated with enterovirus infections. J. Inf. Dis., 175:554-560. Lönnrot, M., Knip, M., Roivianen, M., Koskela, P., Åkerblom, H.K., and Hyöty, H., (1998) Onset of type 1 diabetes mellitus in infancy after enterovirus infections. Diabetic Med., 15:431-434. Valtanen, S., Roivainen, M., and Hovi, T. (1999) Problems with biotin-labelled virions as probes in poliovirus-specific m-capture-IgM assays. J. Clin. Virol., 14:17-23. Viskari, H.R., Roivianen, M., Reunanen, A., Pitkäniemi, J., Sadeharju, K., Koskela, P., Hovi, T., Leinikki, P., Vilja, P., Tuomilehto, J., and Hyöty, H., (2002) Materal first-trimester enterovirus infection and future risk of type 1 diabetes in the exposed fetus. Diabet., 51:2568-2571.