Anti-h LH 5302 SP-1

Catalog Number: 100018

Key Features

Liquid, may turn slightly opaque during storage

Human

LF, CLIA, FIA

Qty:
+ -

Custom Quote

Product Citations

Product Overview
Product NameAnti-h LH 5302 SP-1
Catalog Number100018
DescriptionMonoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
ApplicationLF, CLIA, FIA
Alternative Names
BrandMedix Biochemica
Further Specification
Form/AppearanceLiquid, may turn slightly opaque during storage
Concentration1.0 mg/ml (+/- 10 %)
NotesNilsson et al. (2001) analyzed epitopes of 30 different LH mAbs. Antibody 5302 was classified as belonging to epitope group beta 1, recognizing intact LH, its beta subunit as well as a common variant of LH. Antibody 5302 did not cross react with TSH or FSH but a minor cross reaction with hCG was detected.
IsotypeIgG1
ClonalityMonoclonal
EpitopeBeta 1 as described in Nilsson et al. (2001). Two antibodies binding to the same, or closely located epitopes, belong to the same group and hence cannot be used as a pair in a sandwich assay. Epitope group numbering does not give any detailed information where the epitope is located.
Purity≥ 95 %
Affinity constantKA= 4.8 x 1010 1/M; KD= 2.1 x 10-11 M ( = 21 pM)
Associated Products

Native LH antigen 996-31

Buffer0.9 % NaCI, 0.095 % NaN3 as a preservative
IEF Profile5.6–6.3
Cross ReactivityLH α 10 %, LH β 127 %, FSH 3 %, hCG 4 %, TSH 0.02 %
SpecificityAntibody recognizes human luteinizing hormone (lutropin), and its beta-subunit
Storage and Shipping
Storage +2-8°C
ShippingCold packs
Shelf Life36 months
References
References

Federici, M.M., Fraser, R., Lundqvist, C., and Lankford, J.C., (1982) Production and characterization of monoclonal antibodies human lutenizing hormones. Fed. Proc., 41

Nilsson, C., Seppälä, M., and Pettersson, K., (2001) Immunological characterization of human luteinizing hormone with special regard to a common genetic variant. J.Endocrinol. 168:10-116