Anti-h PSA 8312 SPRN-5
Catalog Number: 100139
Key Features
Liquid, may turn slightly opaque during storage
Human
FIA
Custom Quote
- Bulk or bespoke? We IVDo that
Request a call back - to discuss your information requirements
Key Documents
Product Overview
| Product Name | Anti-h PSA 8312 SPRN-5 |
|---|---|
| Catalog Number | 100139 |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Application | FIA |
Further Specification
| Form/Appearance | Liquid, may turn slightly opaque during storage |
|---|---|
| Concentration | 5.0 mg/ml (+/- 10 %) |
| Notes | Clone 8312 reacts with non-reduced and reduced intact PSA as well as with reduced PSA fragments (Rye et al., 1999). In the same study affinities for free-PSA and PSA-ACT-complex were, 7.5 x 10-9 mol/l and 1.03 x 10-10, respectively. They also noted that antibodies binding to epitope group 6 form a good pair with antibodies from groups 1 and 3. Clone 8312 crossreacts with human kallikrein-2 (Rye, 1999a). Clone 8312 was coded as 5E4 in Rye et al. (1999). |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Epitope | Residues 3–11, group 6a as described in Rye et al. (1999) |
| Purity | ≥ 95 % |
| Affinity constant | KA= 3 x 109 1/M |
| Associated Products | Native PSA antigen, Medix Biochemica 497-11 and native PSA-ACT complex, Medix Biochemica 498-11. |
| Buffer | 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| IEF Profile | 6.3–7.0 |
| Cross Reactivity | PSA/α1-ACT complex 15 %. Does not recognize human kallikrein-2 or PAP. |
| Specificity | Antibody recognizes human prostate-specific antigen |
Storage and Shipping
| Storage | +2-8°C |
|---|---|
| Shipping | Cold packs |
| Shelf Life | 36 months |
References
| References | Rye, P.D., Bormer, O.P. and Paus, E. (guest editors) (1999), ISOBM TD-3 International Workshop on monoclonal antibodies against prostate-specific antigen. Tumor Biol., 20(suppl 1):1-94 |
|---|