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Anti-h PSA 8312 SPRN-5

Catalog Number: 100139

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Key Features

Form :

Liquid, may turn slightly opaque during storage

Species Reactivity :

Human

Application :

FIA

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Key Documents

Product Specification

Product Citations

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Product Overview

Product Name	Anti-h PSA 8312 SPRN-5
Catalog Number	100139
Description	Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
Application	FIA
Brand	Medix Biochemica

Further Specification

Form/Appearance	Liquid, may turn slightly opaque during storage
Concentration	5.0 mg/ml (+/- 10 %)
Notes	Clone 8312 reacts with non-reduced and reduced intact PSA as well as with reduced PSA fragments (Rye et al., 1999). In the same study affinities for free-PSA and PSA-ACT-complex were, 7.5 x 10-9 mol/l and 1.03 x 10-10, respectively. They also noted that antibodies binding to epitope group 6 form a good pair with antibodies from groups 1 and 3. Clone 8312 crossreacts with human kallikrein-2 (Rye, 1999a). Clone 8312 was coded as 5E4 in Rye et al. (1999).
Isotype	IgG1
Clonality	Monoclonal
Epitope	Residues 3–11, group 6a as described in Rye et al. (1999)
Purity	≥ 95 %
Affinity constant	KA= 3 x 10⁹ 1/M
Associated Products	Native PSA antigen, Lee Biosolutions 497-11 and 497-17, and native PSA-ACT complex, Lee Biosolutions 498-11
Buffer	37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
IEF Profile	6.3–7.0
Cross Reactivity	PSA/α1-ACT complex 15 %. Does not recognize human kallikrein-2 or PAP.
Specificity	Antibody recognizes human prostate-specific antigen

Storage and Shipping

Storage	+2-8°C
Shipping	Cold packs
Shelf Life	36 months

References

References	Rye, P.D., Bormer, O.P. and Paus, E. (guest editors) (1999), ISOBM TD-3 International Workshop on monoclonal antibodies against prostate-specific antigen. Tumor Biol., 20(suppl 1):1-94