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Anti-h TSH 5405 SP-5

Catalog Number: 100819

Key Features

Liquid, may turn slightly opaque during storage

Human

LF, CLIA, FIA

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Key Documents

Product Overview
Product Name Anti-h TSH 5405 SP-5
Catalog Number 100819
Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
Application LF, CLIA, FIA
Brand Medix Biochemica
Further Specification
Form/Appearance Liquid, may turn slightly opaque during storage
Concentration 5.0 mg/ml (+/- 10 %)
Notes Wu et al. (2002) developed a three antibody assay system which utilizes clones 5403, 5404 and 5405. Clone 5405 was used as a coated antibody and clones 5403 and 5404 were used as biotinylated label antibodies. They were able to achieve 0.002 mIU/L analytical and 0.017 mIU/L functional sensitivity. The test had negligible cross-reactivity with LH, FSH and hCG which were tested up to 200 mIU/L and 2500 IU/L, respectively.
Isotype IgG2a
Clonality Monoclonal
Epitope Group 3
Purity ≥ 95 %
Affinity constant KA= 6.6 x 109 1/M; KD= 1.5 x 10-10 M (= 0.15 nM)
Associated Products

Native TSH antigen 996-51

Buffer 0.9 % NaCI, 0.095 % NaN3 as a preservative
IEF Profile 6.2–7.1
Cross Reactivity TSH α 9.3 %, hCG < 0.1 %, LH 0.47 %, FSH 1.8 %
Specificity Antibody recognizes human thyrotropin and its free beta subunit
Storage and Shipping
Storage +2-8°C
Shipping Cold packs
Shelf Life 36 months
References
References Wu, F.-B., Han, S.-Q. and He, Y.-F. (2002) Time-resolved immunofluorometry of serum hTSH with enhanced sensitivity. J. Immunoassay & Immunochem., 23(2):191-210