Anti-hCG beta 5008 SP-5
Catalog Number: 100006
Key Features
Liquid, may turn slightly opaque during storage
Human
FIA
Following pairs are especially recommended for free hCG beta CLIA assays:
(capture) – (detection)
hCG 5012 – hCG 5004
hCG 5012 – hCG 5008
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Key Documents
Product Overview
| Product Name | Anti-hCG beta 5008 SP-5 |
|---|---|
| Catalog Number | 100006 |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Application | FIA |
Further Specification
| Form/Appearance | Liquid, may turn slightly opaque during storage |
|---|---|
| Concentration | 5.0 mg/ml (+/- 10 %) |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Epitope | Beta-2 as described in Berger et al. (2013). The antibody recognizes both intact hCG and free β subunit. |
| Purity | ≥ 95 % |
| Affinity constant | hCG: KA= 2.9 x 1010 1/M; KD= 3.4 x 10-11 M (= 0.03 nM) hCGb: KA= 4.4 x 109 1/M; KD= 2.3 x 10-10 M (= 0.23 nM) |
| Associated Products | Native hCG antigens, Lee Biosolutions 189-10 and 189-11 |
| Buffer | 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| IEF Profile | 6.6 – 7.8 |
| Cross Reactivity | Does not recognize hCGα, LH, FSH, or TSH |
| Specificity | Antibody recognizes human chorionic gonadotropin and its free beta subunit |
Storage and Shipping
| Storage | +2-8°C |
|---|---|
| Shipping | Cold packs |
| Shelf Life | 36 months |
References
| References | Berger, P., Paus, E., Hemken, P.M., Sturgeon, C., Stewart, W.W., Skinner, J.P., Harwick, L.C., Saldana, S.C., Ramsay, C.S., Rupprecht, K.R., Olsen, K.H., Bidart, J.M. and Stenman, U.H. (2013) Candidate epitopes for measurement of hCG and related molecules: the second ISOBM TD-7 workshop. Tumor Biol., 34: 4033-4057 |
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