The diagnosis and monitoring of cancer is a complex process, requiring the application of biomarkers to identify tumors, investigate their origins and monitor their development. Rapid access to the right reagents for these biomarkers is vital in order for you to develop and manufacture high-quality immunoassays that are needed to monitor cancer patients’ health after initial treatment.
Our portfolio provides a single source of antibodies, antigens, and validation biospecimens for your cancer marker immunoassay development projects, meaning you have rapid access to the critical raw materials you need.
Many of these raw materials are already validated and widely used in IVD test development. We also provide many emerging cancer-associated markers. These include:
Carcinoembryonic antigen (CEA)
Marker to monitor the re-occurrence of a wide range of cancers, including: colorectal cancer, bladder, breast, lung, ovarian, pancreatic, stomach and thyroid.
Neuron-specific enolase (NSE)
Follow-up marker for neuron-specific enolase-secreting tumors, including: neuroblastoma, small-cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors and melanoma.
Squamous cell carcinoma antigen (SCC)
An endogenous protease inhibitor that has elevated expression levels in several cancer types.1 Ideal for monitoring: small-cell lung cancer, cervical cancer, and head and neck cancers.
In addition, we supply both monoclonal antibodies and native or recombinant antigens for other markers, including: PSA, CA 15-3, CA 125, CA 19-9, CA 72-4, CA 50, CA 242, CYFRA 21-1, hemoglobin, AFP and S100B.
Discover all our tumor markers:
1. Suminami, Y., Nagashima, S., Vujanovic, N et al. Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1. Br J Cancer. 2000;82:981–989.
Patient samples suitable for cancer assay validations
We also offer a wide range of biological materials to provide patient samples suitable for cancer assay validations.
Patient samples – serum:
- Breast cancer 991-24-S-B
- Prostate cancer 991-24-S-PC
- Colon cancer 991-24-S-COC
- Lung cancer 991-24-S-LC
Patient samples – plasma:
- Breast cancer 991-58-S-BC
- Prostate cancer 991-58-S-P
Healthy control biospecimens – ideal for use in biological matrices or negative controls:
- 991-24-P (bulk)
- 991-24-PS (healthy control samples)*
- 991-58-S / 991-58-P-RC (bulk source / recovered)
- 991-58-PS (healthy control samples)*
*Healthy controls can typically be age / gender matched. Contact our team for more information.